Antonym of FACSIMILE

Answer: Option C

Facsimile : an exact copy, especially of written or printed material.
Reproduction : the action or process of copying something.
Sincere : free from pretence or deceit; proceeding from genuine feelings.
Original : the earliest form of something, from which copies may be made.
Engineered : (of an organism) modified by manipulation of genetic material.

Antonym of Facsimile is Original