Antonym of SANCTIFY

Answer: Option D

Sanctify : set apart as or declare holy.
Dedicate : devote (time or effort) to a particular task or purpose.
Patronise : treat in a way that is apparently kind or helpful but that betrays a feeling of superiority.
Venerate : regard with great respect; revere.
Pollute : contaminate (water, the air, etc.) with harmful or poisonous substances.

Antonym of Sanctify is Pollute