Q570
'Colchicine' interferes with
A.
Replication
B.
Recombination
C.
Formation of spindle fibres
AnswerD.
All of these
Answer: Option C
Solution
Answer: Option C
Solution:
'Colchicine' interferes with the Formation of spindle fibres.The alkaloid drug, colchicine, extracted from the corm of the autumn crocus (Colchicum autumnale), arrests mitosis in metaphase by interfering with the formation of spindle fibrils, thereby retarding the division of the centromeres and preventing the division of the centrioles.