Q934
Inhibitors to cell membrane synthesis are
A.
Polymixin
B.
Gramicidin and Circulin
C.
Tyrocidin
D.
All of the above
AnswerAnswer: Option D
Solution
Answer: Option D
Solution:
Inhibitors to cell membrane synthesis are Polymixin, Gramicidin, and Circulin, also Tyrocidin.Polymyxin antibiotics inhibit bacterial membranes after binding to lipopolysaccharides (LPSs), interacting with lipid A of the outer membrane, and acting as a detergent by disrupting the membrane phospholipids, causing cellular permeability and demise.
Gramicidin and circulin are antibiotic peptides that can be incorporated into the monolayers of cell membranes.
Tyrocidine is a mixture of cyclic decapeptides produced by the bacteria Bacillus brevis found in soil.