Mr. Khanna is held in high esteem by the residents of the colony.

Answer: Option C

Esteem : respect and admiration.
Revere : feel deep respect or admiration for (something).
Hatred : intense dislike; hate.
Disdain : the feeling that someone or something is unworthy of one's consideration or respect.
Notoriety : the state of being famous or well known for some bad quality or deed.

Antonym of Esteem is Disdain