Overeating can often be detrimental.

Answer: Option A

Detrimental : tending to cause harm.
Beneficial : resulting in good; favourable or advantageous.
Injurious : causing or likely to cause damage or harm.
Useful : able to be used for a practical purpose or in several ways.
Destructive : causing great and irreparable damage.

Antonym of Detrimental is Beneficial