Tolerance is the essence of religion.

Answer: Option C

Tolerance : the ability or willingness to tolerate the existence of opinions or behaviour that one dislikes or disagrees with.
Impatience : the tendency to be impatient; irritability or restlessness.
Cruelty : cruel behaviour or attitudes.
Bigotry : intolerance towards those who hold different opinions from oneself.
Indifference : lack of interest, concern, or sympathy.

Antonym of Tolerance is Bigotry