Vanity never plays in the long run.

Answer: Option D

Vanity : excessive pride in or admiration of one's own appearance or achievements.
Profanity : a swear word; an oath.
Conceit : excessive pride in oneself.
Pretence : an attempt to make something that is not the case appear true.
Humility : the quality of having a modest or low view of one's importance.

Antonym of Vanity is Humility