What is the effect of Digoxin on heart rate?

Answer: Option A

Digoxin is a medication used primarily in the treatment of heart failure and atrial arrhythmias.

One of its key effects is to decrease the heart rate by increasing vagal tone, which slows down the conduction through the atrioventricular (AV) node.

This leads to a reduction in the heart rate, which is particularly beneficial in conditions like atrial fibrillation where the heart rate is abnormally high.

Digoxin also increases the force of contraction of the heart muscle, making it more efficient at pumping blood.

Therefore, the correct effect of Digoxin on the heart rate is decrease.