Which one of the following is INCORRECT about protein structures?
A. A protein fold is stabilized by favorable noncovalent interactions
B. All parts of a fold can be classified as helices, strands or turns
C. Two non-covalent atoms cannot be closer than the sum of their van der Waals radii
D. The peptide bond is nearly planar
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Which one of the following amino acids has three ionizable groups?
A. Glycine
B. Leucine
C. Valine
D. Lysine
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During lactic acid fermentation, net yield of ATP and NADH per mole of glucose is
A. 2 ATP and 2 NADH
B. 2 ATP and 0 NADH
C. 4 ATP and 2 NADH
D. 4 ATP and 0 NADH
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The reactions leading to the formation of amino acids from the TCA cycle intermediates are
A. Carboxylation
B. Isomerization
C. Transamination
D. Decarboxylation
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The catalytic efficiency for an enzyme is defined as
A. K c a t
B. k c a t V m a x
C. K M k c a t
D. v m a x K c a t
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Which of the following types of molecules act as biological catalysts?
P. Protein
Q. RNA
R. Phospholipid
A. P and Q only
B. P and R only
C. Q and R only
D. P, Q and R
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Which one of the following amino acids has the highest probability to be found on the surface of a typical globular protein in aqueous environment?
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Determine the correctness or otherwise of the following Assertion (A) and the Reason (R) .
Assertion: A very low amount of inhibitor can act as an activator for allosteric enzymes.
Reason: Allosteric enzymes follow Michaelis-Menten kinetics.
A. Both (A) and (R) are true and (R) is the correct reason for (A)
B. Both (A) and (R) are true but (R) is not the correct reason for (A)
C. (A) is true but (R) is false
D. (A) is false but (R) is true
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During photorespiration under low CO2 and high O2 levels, O2 reacts with ribulose 1, 5-bisphosphate to yield
A. One molecule each of 3-phosphoglycerate and 2-phosphoglycolate
B. Two molecules of 3-phosphoglycerate
C. Two molecules of 2-phosphoglycolate
D. One molecule each of 3-phosphoglycerate and glyoxylate
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The activity of an enzyme is expressed in International Units (IU). However, the SI unit for enzyme activity is Katal. One Katal is
A. 1.66 × 104 IU
B. 60 IU
C. 6 × 107 IU
D. 106 IU
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The molarity of water in a water: ethanol mixture (15 : 85, v/v) is approximately
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The product(s) resulting from the hydrolysis of maltose is/are
A. A mixture of α-D-Glucose and β-D-Glucose
B. A mixture of D-Glucose and L-Glucose
C. α-D-Glucose only
D. β-D-Glucose only
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Match the vitamins in
Group I with the processes/ reactions in
Group II .
Group I
Group II
P. Pantothenic acid
1. Electron transport
Q. Vitamin B2
2. Transfer of 1-C units
R. Vitamin B6
3. Decarboxylation
S. Folic acid
4. Fatty acid metabolism
5. Hydrolysis
A. P-5, Q-2, R-4, S-1
B. P-4, Q-1, R-3, S-2
C. P-4, Q-2, R-1, S-3
D. P-2, Q-1, R-3, S-5
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An alternative to glycolysis pathway is
A. Glyoxylate pathway
B. Pentose phosphate pathway
C. Citric acid cycle
D. Gluconeogenesis
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Disaccharide molecules that contain β(1→ 4) glycosidic linkage are
A. Sucrose and maltose
B. Sucrose and isomaltose
C. Maltose and isomaltose
D. Lactose and cellobiose
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The dissociation constant Kd for ligand binding to the receptor is 10-7 M. The concentration of ligand required for occupying 10% of receptors is
A. 10-6 M
B. 10-7 M
C. 10-8 M
D. 10-9 M
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Which one of the following metabolic processes in mammalian cells does NOT occur in the mitochondria?
A. Citric acid cycle
B. Oxidative phosphorylation
C. Fatty acid β-oxidation
D. Glycolysis
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The ΔG° for the oxidation of NADH by FAD is
A. -9.25 kJ mol-1
B. -103.04 kJ mol-1
C. +51.52 kJ mol-1
D. -18.5 kJ mol-1
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Match the high energy compounds in
Group I with the biosynthetic pathways for the molecules in
Group II .
Group I
Group II
P. GTP
1. Fatty acid
Q. UTP
2. Phospholipid
R. CTP
3. Protein
S. Acyl coenzyme A
4. Peptidoglycan
A. P-3, Q-2, R-4, S-1
B. P-2, Q-4, R-3, S-1
C. P-4, Q-3, R-1, S-2
D. P-3, Q-4, R-2, S-1
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If a plant is shifted to cold temperature, which of the following changes would take place in its membrane?
A. Ratio of unsaturated to saturated fatty acids would increase
B. Ratio of unsaturated to saturated fatty acids would decrease
C. Absolute amount of both fatty acids would increase keeping the ratio same
D. Absolute amount of both fatty acids would remain unchanged
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