The enzyme which synthesize RNA primer for DNA synthesis is
A. DNA primase
B. Primase
C. Primer synthase
D. All of the above
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The role of guide RNA (gRNA) is recognized in
A. RNA editing
B. Antisense RNA
C. RNA splicing
D. All of the above
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The form or conformation of DNA double helix which is prevalent in vivo is
A. B-DNA
B. A-DNA
C. Z-DNA
D. All of the above
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The sugar residues are covalently joined by
A. 5' → 3' phosphodiester bonds
B. H2 bonds
C. Phosphorylated ions
D. Covalent bonds
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The daughter cells receive duplex DNA as
A. Both strands from parents
B. Both strands are newly synthesized
C. One from parent and one is newly synthesized
D. Can not be predicted
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Molecular markers are useful in
A. Gene or disease marker maps
B. Gene tracking
C. Marker-marker mapping
D. All of the above
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In eukaryotes, which DNA polymerase is involved in extending the RNA primer and providing template for an accessory factor and replication factor, which control the processivity in lagging strand?
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Which one of the following base is present only in DNA?
A. Thymine
B. Uracil
C. 5-methylcytosine
D. Inosine
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Kinase reactions
A. Inhibit ATP breakdown
B. Involve the addition or removal of a phosphate group
C. Involve the addition or removal of a ketone group
D. Involve the addition or removal of an amino acid to a polypeptide chain
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The backbone of double helix DNA is
A. Sugar phosphate units
B. Nitrogenous bases
C. Nucleosides
D. All of the above
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Homologous genes present in different organisms are called
A. Paralog
B. Duplicate genes
C. Ortholog
D. Xenolog
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The C-value paradox may be explained by the
A. More number of genes with more complexity
B. Predominance of non-coding DNA
C. Both A and B
D. Non existence of coding regions
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A virus whose RNA genome has a DNA intermediate as part of its replication cycle
A. Retro virus
B. Cauliflower mosaic virus
C. Vaccinia virus
D. Adenovirus
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In most bacterial mRNAs, the initiation codon is preceded by a special sequence called
A. 5'-Methylguanosine cap
B. Poly A tail
C. Ribosome binding site
D. A and B both
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Proteins transported to nucleus requires
A. Nuclear localization sequences
B. N-terminal transit sequence
C. Transit peptide
D. All of the above
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In E. coli, if there is no CCA at 3' end tRNA, it will be added by the enzyme
A. tRNA nucleotidyl transferase
B. Transposase
C. Nuclease
D. All of the above
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Which one of the following is not directly involved in the process known as translation?
A. Peptidyl transferase
B. Aminoacyl-tRNA synthetases
C. mRNA
D. DNA
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Which of the following statement about eukaryote RNA polymerases is correct?
A. RNA polymerase I (RNA Pol I) is located in the nucleolus and transcribes the 28S, 18S, 5.8S rRNA genes
B. RNA polymerase II (RNA Pol II) is located in the nucleoplasm and transcribes protein coding genes to yield pre-mRNA and also the genes encoding small nuclear RNAs (snRNA) involved in RNA processing
C. RNA polymerase III (RNA Pol III) is located in the nucleoplasm and transcribes genes for tRNA, 5S rRNA, and the 7S rRNA
D. All of the above
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The 5' upstream of a transcription start contains
A. Poly A tail
B. Promoter
C. Intron
D. Exon
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Open promoter complex comprises
A. RNA polymerase bound on cis acting element promoter
B. local unwinding of DNA at active genic region
C. Both A and B
D. Proteins started to open up chromatin
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