What is the effect of strychnine sulphate on spinal cord?
A. Stimulation
B. Depression
C. Contraction
D. Relaxation
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Drug administered through the following route is most likely to be subjected to the firstpass metabolism
A. Oral
B. Sublingual
C. Subcutaneous
D. Rectal
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Which of the following is the safest anaesthetics?
A. Halothane
B. Ether
C. Cyclopropane
D. Nitrous oxide
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The therapeutic response to antidepressant drugs is usually over a period of
A. 2 - 3 Days
B. 2 - 3 Weeks
C. 24 Hours
D. 2 - 3 Month
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Presently, Penicillin is obtained from a high yielding mutant of . . . . . . . .
A. P. notatum
B. P. falciparum
C. P. chrysogenum
D. T. pallidum
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Drug prevents mast cells granulation in Asthma is:
A. Ipratropium Br
B. Nedocromil Na
C. Levalbuterol
D. Fluticasone
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Potassium sparing diuretics block . . . . . . . . channels in the luminal membrane of the principal cells in the late distal tubule and collecting duct.
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Which one is an advantage of oral route of administration?
A. Sometimes complete drug is not absorbed
B. Economical, sterilisation is not required
C. Unpleasant taste of drugs
D. Not effective in emergencies
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Pick out the appropriate alimentary route of administration when passage of drugs through liver is minimized:
A. Oral
B. Transdermal
C. Rectal
D. Intraduodenal
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The following Ergot derivative is used for treatment of acute migraine attack
A. Paracetamol
B. Sumatriptan
C. Ergotamine
D. Metoclopramide
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Phenylbutazone is a potent
A. Anti pyretic
B. Anti inflammatory agent
C. Anti septic
D. None of the above
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Stilboestrol belongs to
A. Synthetic estrogen
B. Semi synthetic estrogen
C. Natural oestrogen
D. None of these
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All are centrally acting muscle relaxant except:
A. Baclofen
B. Tizanidine
C. Dantrolene
D. Benzodiazepine
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. . . . . . . . is found in rich amounts in the neuromuscular junction, postganglionic parasympathetic nerve terminal and ANS ganglia.
A. True choline esterase
B. Butyryl choline esterase
C. Pseudocholine esterase
D. Acetylcholinesterase
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. . . . . . . . drug has promising in-vitro and in-vivo activity against strains of Mycobacterium avium Complex.
A. Rifabutin
B. Clarithromycin
C. Azithromycin
D. Ciprofloxacin
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The drug used as an analeptic is
A. Nikethamide
B. Amphetamine
C. Bemegride
D. All the above
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Drug used to test gastric acid secretion
A. Dexamethasone
B. Tyramine
C. Mannitol
D. Histamine
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Gatifloxacin has been withdrawn from market becuase.
A. Causes renal failure
B. Causes peripheral vascular disease
C. Causes erectile dysfunction
D. Hyperglycemia in elderly
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Which among the following is an antifilarial drug?
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The mechanism of vigabatrin's action is:
A. Direct action on the GABA receptorchloride channel complex
B. Inhibition of GABA aminotransferase
C. NMDA receptor blockade via the glycine binding site
D. Inhibition of GABA neuronal reuptake from synapses
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