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Biotechnology Engineering · all questions

Computational Tools in Biotechnology
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The method used for prediction of three-dimensional structure of a protein from known structure(s) of one or more related proteins is

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Which one of the following BLAST search programs is used to identify homologs of a genomic DNA query in a protein sequence database?

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The multiple sequence alignment tool is . . .

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How many rooted and unrooted phylogenetic trees, respectively, are possible with four different sequences?

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Identify the file format given below:
>P1; JMFD
Protein X - Homo sapiens
MKALT ARQQEVFDLIRDHISRTLRQQGDWL

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The compound that has properties to become a drug is known as . . .

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Which one of the following tools is used to compare all the possible six-open reading frames of a given nucleotide query sequence with all the available six-open reading frames of the nucleotide sequence database?

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In bioinformatics, the term 'BLAST' refers to

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Determine the correctness or otherwise of the following Assertion (A) and the Reason (R).
Assertion: Ab initio gene finding algorithms that predict protein coding genes in eukaryotic genomes are not completely accurate.
Reason: Eukaryotic splice sites are difficult to predict.

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While searching a database for similar sequences, E-value does not depend on the

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The most widely used program for multiple sequence alignment is

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The study of evolutionary relationships is known as

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Program used for essentially local similarity search is

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The length of the minimum unique stretch of DNA sequence that can be found only once in a 3 billion base pairs long genome is

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Which of the following statements are CORRECT when a protein sequence database is searched using the BLAST algorithm?
P. A larger E-value indicates higher sequence similarity.
Q. E-value < 10-10 indicates sequence homology.
R. A higher BLAST score indicates higher sequence similarity.
S. E-value > 10-10 indicates sequence homology.

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Which one of the following is a database of protein sequence motifs?

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Which of the following is a model organism database?

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Accession number is a unique identification assigned to a

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An example of a derived protein structure database is

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The suitable substitution matrix to align closely related sequences is

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