Identify the character-based method(s) used for the construction of a phylogenetic tree.
A. Q only
B. P and R only
C. Q and S only
D. S only
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An example of a program for constructing a phylogenetic tree
A. PHYLIN
B. Phrap
C. ProDom
D. PHDsec
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Amino acid sequences of cytochrome c and ribulose 5-phosphate epimerase from 40 organisms were chosen and phylogenetic trees were obtained for each of these two protein families.Assertion [A] and the Reason [R] .Assertion [A]: The two trees will not be identical.Reason [R]: The nature and frequency of mutations in the two families are different.
A. Both [A] and [R] are true and [R] is the correct reason for [A]
B. Both [A] and [R] are true but [R] is not the correct reason for [A]
C. Both [A] and [R] are false
D. [A] is false but [R] is true
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Match the items in
Group I with an appropriate description in
Group II .
Group I Group II
P. UPGMA
1. Protein sequence database
Q. CLUSTAL
2. Phylogenetic analysis
R. SWISS-PROT
3. 3-D structure visualization
S. RasMol
4. Multiple sequence alignment
A. P-4, Q-1, R-2, S-3
B. P-2, Q-4, R-1, S-3
C. P-2, Q-3, R-1, S-4
D. P-2, Q-1, R-4, S-3
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Number of unrooted trees in a phylogeny of five sequences is
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Which one of these is a nucleotide sequence data base?
A. TREMBL
B. EMBL
C. SWISS
D. PROSITE
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The term "Flybase" is a . . .
A. Model organism database
B. Biodiversity database
C. Biomolecular database
D. Literature database
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The algorithm for BLAST is based on
A. Dynamic Programming
B. Hidden Markov Model
C. k-tuple analysis
D. Neural Network
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The process in which macromolecules are released out of cells is known as . . .
A. Exocytosis
B. Pinocytosis
C. Phagocytosis
D. Endocytosis
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PDB is a . . .
A. Composite database for sugar
B. Dimensional database for micromolecules
C. Primary database for macromolecules
D. Electrophoresis database
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For prediction of three-dimensional structure of protein
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Carl Woese used the gene sequence of which one of the following for phylogenetic taxonomy of prokaryotes?
A. A ribosomal RNA of large ribosomal subunit
B. A ribosomal RNA of small ribosomal subunit
C. A ribosomal protein of large ribosomal subunit
D. A ribosomal protein of small ribosomal subunit
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The retrivel and search tool of the NCBI is . . .
A. Sakura
B. Webin
C. Entrez
D. None of these
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Which one of the following is not an algorithm for building phylogenetic trees?
A. Maximum parsimony
B. Neighbor joining
C. Maximum likelihood
D. Bootstrap
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Which one of the following methods is used to test the significance of a predicted phylogeny?
A. Bootstrap
B. Maximum likelihood
C. Maximum parsimony
D. Minimum evolution
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The amino acid substitution matrices in decreasing order of stringency for comparing protein sequences are
A. PAM250, PAM120, PAM100
B. PAM100, PAM120, PAM250
C. PAM250, PAM100, PAM120
D. PAM120, PAM250, PAM100
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Somethong performed on computer or computer simulation is . . .
A. Insilico
B. Silico
C. Invitro
D. All of these
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Proteomics is the study of . . .
A. Set of carbohydrates
B. Set of proteins
C. Set of specific proteins in the cell
D. Set of entire proteins in a cell
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Match the entries in the
Group I with the entries in
Group II .
Group I Group II
P. Threading
1. Gene duplication
Q. FASTA
2. Fold prediction
R. Profile
3. HMM
S. Paralogs
4. k-tuple
A. P-2, Q-1, R-3, S-4
B. P-2, Q-4, R-3, S-1
C. P-3, Q-4, R-2, S-1
D. P-1, Q-4, R-3, S-2
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Determine the correctness or otherwise of the following Assertion (A) and Reason (R) .Assertion: UPGMA method produces ultrametric tree.Reason: Sequence alignment is converted into evolutionary distances in UPGMA method.
A. Both (A) and (R) are true and (R) is the correct reason for (A)
B. Both (A) and (R) are true and (R) is not the correct reason for (A)
C. (A) is true but (R) is false
D. (A) is false but (R) is true
Select an option to see the answer and solution.
