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Biotechnology Engineering · all questions

Immunology in Biotechnology
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Which one of the following amino acids is catalyzed by activated macrophages to produce reactive nitrogen species?

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Recombinant live attenuated vaccine against hepatitis B was prepared from

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Which of the following statements about immune response are correct?
P. T cells are activated by antigen-presenting cells.
Q. Foreign peptides are not presented to helper T cells by class II MHC proteins.
R. Dendritic cells are referred to as professional antigenpresenting cells.

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Which one of the following complement proteins is the initiator of the membrane attack complex?

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Which class of antibody is first made by developing B cells inside bone marrow?

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Macrophages eliminate pathogenic bacteria upon activation by

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Match the items Group I with Group II.
Group I Group II
P. Programmed cell death at site of infection 1. TMV coat protein
Q. Hormone upregulated during flooding stress 2. EPSP synthase
R. Target for herbicide glyphosate 3. Hypersensitive response
S. Pathogen-derived resistance 4. Ethylene

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Idiotypic determinants of an antibody are associated with the

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Interferon β is produced by

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Junctional diversity of antibody molecules results from

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Determine the correctness or otherwise of the following Assertion (A) and the Reason (R).
Assertion: IgM is found in serum as a pentameric protein consisting of five IgM monomers.
Reason: The pentameric form of IgM is due to cross linking of IgM monomers via peptide bond.

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Which one of the following is NOT a part of the human non-specific defense system?

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Match the immunoglobulin class in Group I with its properties in Group II.
Group I Group II
P. IgG 1. Major antibody in external secretions such as bronchial mucus
Q. IgA 2. Protects against parasites
R. IgE 3. Antibody that appears first in serum after exposure to an antigen
S. IgM 4. Antibody present in highest concentration in serum

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Reverse vaccinology indicates

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Viral replication within cells is inhibited by

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Antibody diversity is generated by

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Match items in Group I with correct options from those given in Group II.
Group I Group II
P. Tissue plasminogen activator 1. Immunomodulator
Q. Gamma interferon 2. Biodegradable plastic
R. Podophyllotoxin 3. Clot dissolution
S. Polyhydroxyalkanoate 4. Anti-tumor agent

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Gram-positive bacteria are generally resistant to complement-mediated lysis because

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Reactions between antibodies and antigens that are detected by precipitate formation in an agar gel are referred as

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Based on the heavy chain, which one of the following antibodies has multiple subtypes?

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