The role of an adjuvant is to
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Biotechnology Engineering · all questionsImmunology in Biotechnology
Immunology in Biotechnology
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Endogenous antigens are presented on to the cell surface along with
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Determine the correctness or otherwise of the following Assertion (A) and Reason (R).
Assertion: An antigen recognized by one immunoglobulin subtype is not recognized by any other subtype.
Reason: Immunoglobulin subtypes differ from each other both in the variable and in the constant regions.
Assertion: An antigen recognized by one immunoglobulin subtype is not recognized by any other subtype.
Reason: Immunoglobulin subtypes differ from each other both in the variable and in the constant regions.
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Nude mice refers to
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Which of the following statement(s) is/are CORRECT for antigen activated effector T cells?
P. CD4+ cells make contact with macrophages and stimulate their microbicidal activity.
Q. CD4+ cells make contact with B cells and stimulate them to differentiate into plasma cells.
R. CD8+ cells make contact with B cells and stimulate them to differentiate into plasma cells.
S. CD8+ cells make contact with virus infected cells and kill them.
P. CD4+ cells make contact with macrophages and stimulate their microbicidal activity.
Q. CD4+ cells make contact with B cells and stimulate them to differentiate into plasma cells.
R. CD8+ cells make contact with B cells and stimulate them to differentiate into plasma cells.
S. CD8+ cells make contact with virus infected cells and kill them.
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Which one of the following mechanisms is used by human pathogens to evade host immune responses?
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Dizygotic twins are connected to a single placenta during their embryonic development. These twins
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Heat inactivation of serum is done to inactivate
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Match the cells in Group I with their corresponding entries in Group II.
| Group I | Group II |
| P. Mast cells | 1. Activation of the complement pathway |
| Q. Natural killer cells | 2. Expression of CD56 |
| R. Neutrophils | 3. Contains azurophilic granules |
| S. Dendritic cells | 4. Defense against helminthic infection |
| 5. Production of antibodies specific to bacteria | |
| 6. Contains long membranous projections |
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The first humanized monoclonal antibody approved for the treatment of breast cancer is
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A humanized antibody is one in which the
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Match the autoimmune diseases in Group I with the corresponding primarily affected organ in Group II.
| Group I | Group II |
| P. Hashimoto's disease | 1. Brain |
| Q. Juvenile diabetes | 2. Pancreas |
| R. Multiple sclerosis | 3. Skeletal muscle |
| S. Myasthenia gravis | 4. Thyroid |
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Which one of the following statements is true with regard to processing and presentation of protein antigens?
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Which of the following cytokines are endogenous pyrogens?
P. Tumor necrosis factor α
Q. Interleukin 1
R. Transforming growth factor β
S. Interleukin 10
P. Tumor necrosis factor α
Q. Interleukin 1
R. Transforming growth factor β
S. Interleukin 10
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B-lymphocytes originate from the bone marrow, whereas T lymphocytes originate from
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Which of the following conditions promote the development of human autoimmune disorders?
P. Inability to eliminate self-reactive lymphocytes
Q. Generation of auto-antibodies
R. Ability to eliminate self-reactive T cells
S. Induction of regulatory T cells in the thymus
P. Inability to eliminate self-reactive lymphocytes
Q. Generation of auto-antibodies
R. Ability to eliminate self-reactive T cells
S. Induction of regulatory T cells in the thymus
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Which one of the following is not a principal component of innate immunity?
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A neonatally thymectomized mouse, immunized with protein antigen shows
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Which of these mice fall to develop a thymus?
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Abzymes are
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