Which one of the combinations of the following statements is true about antibody structure?
P. Limited proteolysis of rabbit IgG with the enzyme pepsin generates two antigen-binding regions (Fab) and an Fc fragment.
Q. Limited proteolysis of rabbit IgG with the enzyme papain generates a single bivalent antigen-binding region F(ab')2 and peptide fragments.
R. The Fc fragment of IgG can self-associate and crystallize into a lattice.
S. The F(ab')2 fragment of IgG is composed of both light and heavy chains.
A. P and Q only
B. P and R only
C. R and S only
D. Q and S only
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Anergy refers to
A. Mitochondrial dysfunction
B. Allergy to environmental antigens
C. Unresponsiveness to antigens
D. A state of no energy
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The polymorphic domains for Class II MHC proteins are
A. α1 and β2 domains only
B. β1 and α2 domains only
C. α1 and β1 domains only
D. α2 and β2 domains only
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ABO blood group antigens in humans are differentiated from each other on the basis of
A. Sialic acid
B. Lipids
C. Spectrin
D. Glycoproteins
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Members of the antibody protein family that have common structural features are collectively known as
A. Haptens
B. Allergens
C. Antigens
D. Immunoglobulins
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In ABO blood group system, antigenic determinants are
A. Nucleic acid
B. Carbohydrate
C. Lipid
D. Protein
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Identification of blood groups involves
A. Precipitation
B. Neutralization
C. Opsonization
D. Agglutination
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Protein A, which has strong affinity to Fc region of immunoglobulin, is extracted from
A. Saccharomyces cerevisiae
B. Staphylococcus aureus
C. Streptococcus pyogenes
D. Streptococcus sanguis
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Lymphocytes interact with foreign antigens in
A. Bone marrow
B. Peripheral blood
C. Thymus
D. Lymph nodes
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Prior exposure of plants to pathogens is known to increase resistance to future pathogen attacks. This phenomenon is known as
A. Systemic acquired resistance
B. Hypersensitive response
C. Innate immunity
D. Antibody mediated response
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