A protein is phosphorylated at a serine residue. A phosphomimic mutant of the protein can be generated by substituting that serine with
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Biotechnology Engineering · all questionsMolecular Biology and Genetics
Molecular Biology and Genetics
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Under alkaline conditions, DNA is more stable than RNA because
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True breeding Drosophila flies with curved wings and dark bodies were mated with true breeding short wings and tan body Drosophila, The F1 progeny was observed to be with curved wings and tan body. The F1 progeny was again allowed to breed and produced flies of the following phenotype, 45 curved wings tan body, 15 short wings tan body, 16 curved wings dark body and, 6 short wings dark body. The mode of inheritance is
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The enzyme which adds phosphate group to the free 5' terminus of a DNA sequence is
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The fundamental feature of the genetic code which allows the expression of a protein in any host is its
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Match the terms in Group I with their possible explanation in Group II
| Group I | Group II |
| P. Orthologs | 1. A cell or an organism, having foreign gene |
| Q. Paralogs | 2. The complement of a protein expressed by a genome |
| R. Proteome | 3. Genes from different species related to each other |
| S. Transgenic | 4. Genes from same species related to each other |
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Which one of the following amino acids in proteins does not undergo phosphorylation?
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In eukaryotes, the ribosomal RNA genes are transcribed by
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The repeat sequence of telomere in humans is
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Match the terms in Group I with their associated functions in Group II.
| Group I | Group II |
| P. Shine-Dalgarno sequences | 1. Aminoacylation of tRNA |
| Q. Leucine zipper | 2. Gene silencing |
| R. Aminoacyl tRNA synthetase | 3. Ribosome binding and facilitation of translation initiation |
| S. RNA interference (RNAi) | 4. Transcription factors |
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In nature, the horizontal gene transfer across bacteria is mediated by
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In tomato plant, red (R) is dominant over yellow (r) for fruit color and purple (P) is dominant over green (p) for stem color. Fruit color and stem color assort independently. The number of progeny plants of different fruit/stem colors obtained from a mating are as follows:
Red fruit, purple stem - 145
Red fruit, green stem - 184
Yellow fruit, purple stem - 66
Yellow fruit, green stem - 47
What are the genotypes of the parent plants in this mating?
Red fruit, purple stem - 145
Red fruit, green stem - 184
Yellow fruit, purple stem - 66
Yellow fruit, green stem - 47
What are the genotypes of the parent plants in this mating?
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Which one of the following covalent linkages exists between 7-Methyl guanosine (m7G) and mRNAs?
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siRNA(s) interfere at
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Determine the correctness or otherwise of the following Assertion (A) and the Reason (R).
Assertion: Isopropylthiogalactoside (IPTG) is a gratuitous inducer of lactose operon.
Reason: Gratuitous inducers are chemical analogs which behave like natural inducer but they do not serve as substrate for the enzymes that are subsequently synthesized.
Assertion: Isopropylthiogalactoside (IPTG) is a gratuitous inducer of lactose operon.
Reason: Gratuitous inducers are chemical analogs which behave like natural inducer but they do not serve as substrate for the enzymes that are subsequently synthesized.
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Hypophosphatemia is manifested by an X-linked dominant allele. What proportion of the offspring from a normal male and an affected heterozygous female will manifest the disease?
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Match the classes of RNA molecules in Group I with their functions in Group II.
| Group I | Group II |
| P. snoRNA | 1. Protects germline from transposable elements |
| Q. piRNA | 2. Blocks translation of selected mRNA |
| R. miRNA | 3. Template for telomere elongation |
| S. snRNA | 4. Modification and processing of rRNA |
| 5. Splicing of RNA transcripts |
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Reverse genetics means
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The cellular process which utilizes RNA-induced silencing complex to block gene expression is
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Match the type of chromosomal inheritance (Column I)
with the corresponding genetic disease or trait (Column II).
| Column I | Column II |
| P. Autosomal recessive inheritance | 1. Huntington disease |
| Q. Autosomal dominant inheritance | 2. Hairy ears |
| R. X-linked inheritance | 3. Cystic fibrosis |
| S. Y-linked inheritance | 4. Hemophilia |
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